In the early morning hours, two elderly whores go back to their hovels. They are not tired from working. They are tired of not doing do. One has problems at home with her teenage daughter and her cross dressing husband. The other, with her loneliness. But that night, they have a date to celebrate the victory in the ring of two wrestlers, twin midgets wearing masks. At the hourly hotel, in order to rob the tiny men of their earnings, they drug them with eye drops. But the dose proves fatal. They murder them unintentionally. Scared and confused, they decide to hide from the police and run away together to live, as they always have, on Bleak Street.

Just by watching Lupe stuck at home in her robe and slippers, no one would will guess that in the 80's she was a rock star. Gone are the times of concerts, fame and success. Agoraphobia does not let her leave home. She depends entirely on Paquita, his mother, a superstitious Mexican, with a huge heart, which not only takes care of his daughter but also her teenage grandson. The problem is that Paquita is running out of time and she doesn't want to leave without getting her daughter back.

Nadine, a beautiful lawyer from Chicago, travels alone to Tijuana, Mexico in search of her missing sister. Her investigation presents unsettling encounters leading her on a mind-bender as she attempts to unravel the compelling truth.